Resources Myths
Seven common myths
Seven things people often hear about small doses, answered plainly.
Myth: more is better
There is no prize for starting high. A higher tier is not a better tier, only a different day.
We recommend finding the lowest tier that suits you, and staying there.
Myth: a dose this small cannot cause harm
Small is not the same as harmless. Who you are and what else you take still matter.
In 62 online reports of lithium combined with this family of substances, 47% described a seizure1.
People taking SSRIs or SNRIs often described weaker effects than they expected2. Read our safety guide before your first dose.
Myth: if you feel nothing, take more
At Micro, little or nothing is the design. Do not take a second dose the same day.
If you want more, move up one tier on a later dose day, after several days at Micro. Keep everything else the same.
Myth: the science is settled
It is not, in either direction.
In a placebo-controlled study of 191 people, the microdose and placebo groups did not differ on psychological measures3.
A double-blind study of 34 people found no evidence of better well-being, creativity or thinking4.
A 2022 review of 44 studies argued it is too early to say the effects are mostly expectation5. Anyone who promises you a result is ahead of the evidence.
Myth: expectations make no difference
They do. In one study, people who expected the most at the start tended to report the most change6.
That is one more reason to keep notes and keep your conditions steady, so you can see what is really there.
Myth: every day is best
We recommend at least one full day off between dose days.
In a 2025 global survey of people who microdose, the most common pattern among regular users was one day on, two days off7.
Myth: it mixes fine with a drink
We recommend taking our products on their own: no alcohol, no cannabis and no other substance on a dose day.
An evening in place of a drink, never alongside one.
Sources
- 1 Nayak et al., Pharmacopsychiatry, 2021
- 2 Gukasyan et al., Journal of Psychopharmacology, 2023
- 3 Szigeti et al., eLife, 2021
- 4 Cavanna et al., Translational Psychiatry, 2022
- 5 Polito and Liknaitzky, Neuroscience and Biobehavioral Reviews, 2022
- 6 Kaertner et al., Scientific Reports, 2021
- 7 Petranker et al., International Journal of Drug Policy, 2026
These guides are general information for adults, written by Mammoth Mushrooms. They are not medical advice. If you take medication or have a health condition, speak to a pharmacist or doctor first.
